LABORATORY REPORT

Activity 7 : Effect of Exercise on Arterial Pressure and Vascular Resistance

Name:

Instructor:

Date:

PREDICTIONS

1. During exercise:

2. During exercise:

3: During exercise:

MATERIALS AND METHODS

1. Dependent Variable

2. Independent Variable

3. Controlled Variables

4. Identify one variable that was not controlled in this study (not dependent or independent variables; hint: think about possible differences between subjects).

5. SVR was calculated using values for BP, CO, and HR. What instrument was used to measure each of the following?

1. Blood pressure

2. Cardiac output

3. Heart rate

RESULTS

See Table 2: Effe ct of Exercise on Systolic and D iastolic Blood Pressure (SBP, SDP) , Heart Rate ( HR ) , and Stroke Volume ( SV )

See Graph: Resting and Early Post-Exercise SBP and DBP

1. Resting and exercising systolic BP --

a. What was the average resting systolic BP?

b. What was the average exercising systolic BP?

c. The range of normal resting systolic BP for the subjects in this experiment is 115-125 mmHg. Did systolic BP increase, decrease, or not change with exercise?

2. Resting and exercising diastolic BP –

a. What was the average resting diastolic BP?

b. What was the average exercising systolic BP?

c. The range of normal resting diastolic BP for these patients was 75-85 mmHg. Did diastolic BP increase, decrease, or not change with exercise?

See Table 3: Resting and Early Post-Exercising on Mean Arterial Blood Pressure ( MAP ) , Cardiac Output (CO), and Systemic Vascular Resistance (SVR)

See Graph: Resting and Exercising MAP, CO and SVR

3. Resting and Exercising MAP –

a. What was the average resting MAP?

b. What was the average exercising MAP?

c. The range of normal resting MAP for the subjects in this experiment is 88-98 mmHg. Did MAP increase, decrease, or not change with exercise?

4. Resting and Exercising CO –

a. What was the average resting CO?

b. What was the average exercising CO?

c. The range of resting CO for the subjects in this experiment is 4.55-5.55 L/min. Did CO increase, decrease, or not change with exercise?

5. Resting and Exercising SVR –

a. What was the average resting SVR?

b. What was the average exercising SVR?

c. The range of resting SVR for the subjects in this experiment is 10.2-12.03 mmHg per min/L. Did SVR increase, decrease, or not change with exercise?

DISCUSSION

1. Explain what caused the observed changes in systolic BP and MAP with exercise.

2. Compare the resting and exercising systemic vascular resistance values and discuss what causes the observed change with exercise.

3. Explain how the change in MAP and SVR affected blood flow and why this is important.

4. Restate your predictions that were correct and give data from your experiment that support them. Restate your predictions that were not correct and correct them with supporting data from your experiment.

APPLICATION

1. Calcium channel blockers, a type of anti-hypertensive drug, block the entry of calcium into smooth muscle which causes smooth muscle to relax. Explain how this decreases blood pressure.

2. Explain why cutting an arterial vessel will cause a greater loss of blood over the same amount of time than cutting a venous vessel.