Curriculum Vitae

Christopher R. Lopez, Ph. D.

I. General Biographical Information

A. Personal

1. Name: Christopher R. Lopez, Ph.D.

B. Education:

1. Postdoctoral Training:

University of Texas Health Science Center Houston (Houston, TX): 2015 - current

Department Microbiology and Molecular Genetics

Postdoctoral advisor: Nayun Kim, Ph.D.

2. Postdoctoral Training:

Baylor College of Medicine (Houston, TX): 2007 - 2013

Department of Pediatrics, Hematology/Oncology Section

Postdoctoral advisor: Alison Bertuch, M.D., Ph.D.

3. Graduate Education:

Baylor College of Medicine (Houston, TX): Ph.D., Cell and Molecular Biology, 1998 - 2006

Interdepartmental Program in Cell and Molecular Biology

Department of Molecular Virology and Microbiology

Thesis: “Investigating the in vivo role of topoisomerase III in E. coli”

Thesis advisor: Lynn Zechiedrich, Ph.D.

4. Undergraduate Education:

Baylor University (Waco, TX): B.A., Biology, 1992 - 1996

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C. Professional Experience

1. Postdoctoral Associate, UT Health Science Center (Houston, TX) 2015 - current

2. Adjunct Instructor (Biology), Houston Community College (Houston, TX) 2014 - current

3. Visiting Assistant Professor of Biology, Houston Baptist University (Houston, TX) 2013 - 2014

4. Postdoctoral Associate, Baylor College of Medicine (Houston, TX) 2007 - 2013

5. Graduate student, Baylor College of Medicine (Houston, TX) 1998 - 2006

6. Lab Technician, Analysys, Inc. (Austin, TX) 1996 - 1998

II. Teaching Experience

A. Courses taught

1. General Biology I (HCC), lecture and lab

2. Introductory Biology (HBU), lecture and lab

3. Human Anatomy and Physiology I (HBU), lab

4. General Biology I (HBU), lecture and lab

B. University service

Co-sponsor American Red Cross (HBU)

C. Educational and Administrative Software Experience

1. Blackboard

2. McGraw-Hill Connect

3. Pearson Mastering Biology

4. PeopleSoft

III. Research Experience

A. Awards

1. Dean's Award, Baylor College of Medicine, 2002 - 2005

2. Claude W. Smith Award, Cell and Molecular Biology, 2002

3. 2nd Place Award for oral presentation, Molecular Virology & Microbiology Retreat, 2002

4. Best student poster presentation, Molecular Virology & Microbiology Retreat, 2001

5. 3rd place poster presentation, Graduate Student Symposium, Baylor College of Medicine, 2000

B. Past Research Support

Department of Defense Breast Cancer Research Program Predoctoral Fellowship

“A role for topoisomerase III in genomic stability” 2002-2005

C. Publications

1. Hang,L.E., Lopez, C.R., Liu, X., Williams, J., Chung, I., Lei, W., Bertuch, A.A.,and Zhao, X. (2014) Regulation of Ku-DNA Association by YKU70 C-terminal tail and SUMO modification. J Biol Chem, 289(15): 10308-10317.

2. Lopez C.R., Ribes-Zamora A, Indiviglio SM, Williams CL, Haricharan S, et al. (2011) Ku Must Load Directly onto the Chromosome End in Order to Mediate Its Telomeric Functions. PLoS Genet 7(8): e1002233.

3. Yang, S., Lopez, C.R., and Zechiedrich, E.L. (2006) Quorum sensing and multidrug transporters in Escherichia coli. Proc Natl Acad Sci USA, 103: 2386-2391.

4. Lopez, C.R., Yang, S., Deibler, R.W., Ray, S.A., Pennington, J., DiGate, R.J., Hastings, P.J., Rosenberg, S.M., and Zechiedrich, E.L. (2005) A role for topoisomerase III in a recombination pathway alternative to RuvABC. Mol Microbiol, 58: 80-101.

D. Submitted Abstracts

1. Lopez, C.R., Rao,P., and Bertuch, A.A. Novel mechanisms leading to telomere dysfunction and cancer predisposition. Innovations in Cancer Prevention and Research Conference. Austin, TX, October 2012, poster presentation.

2. Lopez, C.R., Ribes-Zamora A., Williams, C.L., Haricharan, S., and Bertuch, A.A. Ku’s direct association with telomeric ends is required for normal telomere structure and function. The Role of telomeres and telomerase in cancer research, American Association for Cancer Research. Ft. Worth, TX, February 2010, poster presentation.

3. Lopez, C.R., Ribes-Zamora, A., Williams, C.L., Haricharan, S., Indiviglio S.M., and Bertuch, A.A. Ku must load onto telomeric ends to mediate its telomeric functions. CSHL Telomeres and telomerase, Cold Spring Harbor, NY, April 2009, platform talk

4. Lopez, C.R., Ribes-Zamora A., Williams, C.L., Haricharan, S., Indiviglio, S.M., and Bertuch, A.A. Assessing the importance of the DNA end binding activity of the Ku heterodimer at telomeres and double strand breaks in Saccharomyces cerevisiae. The Role of telomeres and telomerase in cancer research, American Association for Cancer Research. San Francisco, CA, December 2007, poster presentation.

5. Lopez, C.R., Ray, S.A.,Pennington, J.,Hastings, P.J.,Rosenberg, S.M., and Zechiedrich, E.L. Topoisomerase III acts in a separate pathway from RuvC to prevent genomic instability. Era of Hope Department of Defense Breast Cancer Research Program Meeting. Philadelphia, PA, June 2005, poster presentation.

6. Lopez, C.R., Ray, S.A., Deibler, R.W., and Zechiedrich, E.L. Topoisomerase III acts in same pathway as RecG. 10th Annual Structural Biology Symposium. Galveston, TX, May 2005, poster presentation.

IV. Volunteer and Community Work

1. Den Leader - Cub Scout Pack 197, Fall 2014 - Current

2. Mentor - Spring Branch I.S.D., 2014 - 2015

3. Math and Science Tutor - Tallowood Baptist Church, Summer 2014

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