721 Blood Glucose Testing
Required Reading
Handbook of Nonprescription Drugs, Chapter 47
Objectives
Nonprescription Products
- Demonstrate the steps in obtaining a blood glucose reading with a glucometer.
- Lay out all materials needed
- lancet w/new needle, alcohol wipes, glucose meter, reagent strip
- Clean all non-sterilized surfaces and wash hands with warm water
- load lancet new needle and set depth to proper setting
- deepest settinghealthy, thick skin
- lightest settingolder, thin skin
- allow hand to be punctured to hang down allowing blood to collect in hand
- clean potential site of puncture with alcohol wipe
- should choose side of finger as this contains fewest nerve endings
- puncture cleaned skin site with lancet allowing puncture site to swell with blood
- swelling should reach the approx. size of a pen tip
- if blood not swelling from wound attempt minor milking of site
- if not blood swell attempt puncture on alternate site following same method and should reset lancet for greater depth of puncture
- Present blood swell to the tip of the reagent slip. Do not place blood on strip. Allow capillary action to carry blood up the reagent slip. If enough blood is presented to strip, the reagent strip well will fill
- Insert reagent strip into the glucose monitor and allow the monitor to read level of glucose in blood
- Take reading and compare to known values
- Dispose of sharps to sharp’s container and wipe down instrumentation, lancet device and puncture site with alcohol. Wash hands
- types of meters
- Accu-check Active
- Ascensia Breeze
- Ascensia Elite
- Ascesia Elite XL
- Identify potential causes of inaccurate readings of a glucometer.
- application of to much blood to reagent strip
- aggressive milking
- use of blood from sites other than hands
- lack of frequent calibration
- fever, exercise, extremely hot weather, sauna, Jacuzzi all increase peripheral blood flow
- cold packs, cold extremities slow peripheral blood flow
- waiting to long to apply blood to reagent strip
- increased concentration of clotting factors
- Assemble typical products needed by an insulin dependent diabetic and describe the function of each.
- Insulin injection devices/Aids
- insertion aids
- a spring loaded jacket that fits over the filled syringe to guide the needle into the skin
- needle can be visible or not visible to px dependant on design of auto injector
- some adjust for depth and angle
- size of injector depends on type
- syringe can be prefilled and carried until ready to use
- insulin is temp sensitive
- insulin pens
- look like a writing pen
- use disposable or single use cartridges
- deliver preset or dial-in doses
- require only one hand for operation
- must remind px to replace disposable needle after every use
- jet injectors
- use pressure to force insulin under skin-no needle
- insulin disperses in the subcu layer
- regular needle creates bolus or a pocket of insulin that can only be absorbed on the pocket’s periphery
- first time insulin users must adjust their dose due to faster insulin adsorption
- error can occur if injector not held tightly to skin
- cause less lipotrophy and inflammation then needle
- infusers
- a small flexible catheter inserted and anchored into the subcu tissue
- px attaches syringe to port external to skin
- allows multiple doses of insulin to be given
- remain in place for 24-72 hrs
- px must take exceptional care of insertion site to prevent infection
- pump infusers
- require for tight control of blood glucose
- through injection as already discussed
- or, through pump at ~rate of 0.5-1.0 Unit/hr
- called open-loop
- no mechanical device constantly monitoring
- px must constantly monitor blood glucose
- at least four times per day
- px must determine how much insulin to inject
- Insulin
- Rapid actinghumalog (insulin Lispro), Novolog (insulin aspart)
- bolus given right before meals to handle the immediate increase in blood sugar
- short acting regular insulinHumulin R, Iletin II Regular, Novolin R
- bolus given right before meals to handle the immediate increase in blood sugar
- Intermediate-acting Lente InsulinHumulin L, Lente Iletin II, Novolin L
- establishes a basal level for most of the day
- zinc suspensions
- Intermediate-acting NPH insulin Humulin N, Novolin N, NHP Iletin II
- establishes a basal level for most of the day
- faster onset than Lente intermediate
- Isophane suspensions
- long actionLantus (insulin glargine), Humulin U Ultralentec
- extremely long acting(~24 hrs) basal dose
- use this for a steady state dose
- still use bolus dose ac
- Insulin Mixtures
- Humalog mix 75/25
- 75% insulin Lispro protamine sulfate: 25% insulin Lispro
- Humulin 50/50
- NPH : Regular insulin
- Humulin 70/30
- 70%NPH : 30% regular insulin
- Novolin 70/30
- 70%NPH : 30% regular insulin
- Novolog Mix 70/30
- 70% insulin aspart protamine suspension : 30% insulin aspart
- Glucose meter
- Accu-check Active
- Ascensia Breeze
- Ascensia Elite
- Ascensia Elite XL
- Lancet
- blood
- preferably human and belonging to px
- Identify appropriate sites on the body for insulin injection.
- repeated injection in same site without rotation can cause lipotrophy, other atrophies and fibrosis
- injection sites in decreasing order of absorption
- abdomenupper armsthighships
- physician argument
- some recommend use of all sites in one area before moving therefore stabilizing insulin dose for longest amount of time
- others recommend using only abdomen therefore preventing any absorption variances
- massaging or exercising injection area can increase rate of absorption and affect px glycemic control
- Discuss proper handling and storage of insulin. Demonstrate the proper technique for withdrawing regular and NPH into the same syringe.
- gently roll, not shake, insulin while in vial
- this also allows warming of insulin for injection
- suspensions are susceptible to protein damage with shaking
- only suspensions need to be rolled
- i.e only the cloudy ones
- all insulin preps should be refrigeratedinsulin heat labile protein
- 36-46 degrees F
- px should constantly inspect insulin prep for discoloration or any other visual changes
- when traveling store insulin in cooler with ice or some other cold substance, packing in many layers of clothes can also be used
- NPH is longer acting than the faster acting regular insulin
- draw the regular insulin first and then draw NPH
- regular is clear solution, NPH is cloudy suspension
- any addition of NPH into Regular insulin vial will contaminate and potentially affect the absorption and duration of the regular insulin
- Regular injection into NPH vial will only cause minor change which is acceptable under most conditions+
- When mixing remember to draw an equal amount of air into syringe to account for both volumes of insulin
- e.g. 5 U regular and 3 U NPH draw 8 U air
- would then inject 5 U air into Regular vial and draw out 5 U regular insulin
- would then inject 3 U air into NPH vial and withdraw 3 U NPH
- when making this draw can only inject air if bottle bottom is pointed towards ceiling otherwise will inject regular into NPH
- Demonstrate proper technique for administering a subcutaneous injection.
- sit downpinch up fold of stomach skinpush needle into fold and inject the fold allows easier access to subcu
- Identify different insulin administration devices, and counsel on their use.
- question 3-1
- Discern the effects of concurrent medications on blood glucose control in a diabetic patient.
Exercises
- Test your blood glucose value using at least two different meters available. Make sure you have completely read the instructions for your particular meter, and are prepared for the procedure prior to collecting a sample.
- Use universal precautions and proper disposal procedures when testing your blood glucose value and practicing subcutaneous injections.
- Practice drawing up insulin into a syringe.
- Review the case study provided, and determine any potential drug interactions with the patient’s diabetes treatment.
- Administer a subcutaneous injection of 0.9% sodium chloride to yourself.
Nonprescription: Diabetes Lecture
Learning objectives:
- Describe the prevalence of diabetes (diagnosed and undiagnosed) in the United States.
- Recognize specific populations that have a higher prevalence of diabetes and why.
- Describe how diabetes affects major physiologic systems and why these particular systems are affected.
- Describe symptoms of diabetes and why diabetes causes these symptoms.
- Know a “normal” blood glucose range.
- Differentiate between Type 1, Type 2 diabetes, and prediabetes.
- Describe the current goals and guidelines of therapy for effective management of diabetes.
- Describe the risk factors associated with the development of Type 2 diabetes.
- Define HbA1C and understand its role in diabetes monitoring. Explain why blood glucose tests are more sensitive than urine glucose tests.
- Differentiate between hyperglycemia and hypoglycemia.
- Describe symptoms of hypoglycemia.
- Recommend appropriate prevention and treatment of hypoglycemia.
- Describe the use of oral agents used in the treatment of diabetes.
- Compare the types of insulin used in the treatment of diabetes in terms of onset and duration of action, and place in therapy