7 Keto DHEA
7-keto DHEA is a metabolite of the adrenal hormone DHEA called dehydroepiandrosterone and a better way to take DHEA.
7-Keto DHEA is normal metabolite in the body that can be converted to other active metabolites that don't have hormonal [Oestrogen or testosterone] effects. In other words, 7-Keto DHEA is a bio-identical hormone that is found naturally in the body. Thus your body has the necessary enzymes to metabolize this compound. 7-keto DHEA is produced in the adrenal glands, brain and skin. There are many DHEA metabolites, yet 7-keto seems to be one of the most valuable among them. 7-keto DHEA is regarded with positive creating wellness effects because it works like DHEA but no hormone side effects.
7-Keto DHEA may enhance immune function, decrease muscle loss, decrease stress, increase metabolic rate and accelerate weight loss in healthy adults. Anti-ageing medicine uses 7-keto
Immune Health
7-keto DHEA has also been shown to improve immune function. In the USA the Minnesota Applied Research Center, performed a four-week human clinical trial to determine the effects of 7-keto on elderly men and women. Using 100mg two times a day, the subjects experienced improved immune function, as well as an increase in immune helper cells, increased white blood cells and decreased blood pressure. These doses are higher than recommended but the study clearly showed positive health benefits for 7-Ket DHEA.
Many people understand chronic use of “Steroids” for dease management like asthma and arthritis act like cortisol. They get weight gain, thinning of skin and bone loss. Thus the patient has DHEA drop and cortisol dominance, 7-Keto DHEA has this anti-cortisol effect so can repair and replace the hormone balance.
Weight Loss
7-keto DHEA has clinically been shown to increase metabolism and contribute to healthy weight loss in numerous studies. The reason why 7-keto DHEA contributes to weight loss is by increasing the activity of enzymes that are responsible for fatty acid oxidation. This increased oxidation improves resting metabolic rate (RMR) hence weight loss results.
These enzymes responsible are Acyl CoA-oxidase, malic enzyme, and glycerol-3-phosphate dehydrogenase that increase thermogenesis. A double blind, placebo-controlled study on 30 overweight adults showed a 10kg decrease in body fat, compared to 6kg in placebo. More of the weight lost was body fat in the 7-keto DHEA group. Thyroid hormone was elevated which is a positive side effect in many low Thyroid patients (on t3 only short term), but no other side effects were reported.
Conclusion a good diet and exercise, coupled with 7-keto DHEA has been shown to accelerate fat loss in men and women without any stimulant effect on the body. Anecdotal reports from patients are 10-15mg of 7 keto DHEA is beneficial for weight loss, used for 4 weeks with Low calorie diet and exercise.
Anti-Aging
As a natural metabolite of the hormone DHEA, 7-keto also naturally declines with age. 7-keto DHEA levels rise until age 20. By 30, blood concentrations begin to decline, reducing by up to 50 percent by age 50. Decreases in DHEA and 7-keto can lead to dominance of the stress hormone cortisol, which can contribute to aging and disease. A recent study evaluated the effect of 7-keto DHEA on markers for heart disease. Only 25mg per day for five days significantly raised HDL or good cholesterol. The total cholesterol reduction was low, but the atherogenic index--a measure for risk of cardiovascular disease showed marked improvement. 7-keto DHEA may also help to improve brain function by helping neurons establish contact with others, increasing efficiency in the aging brain. A leading researcher of 7-keto, Dr. Henry Lardy, says that 7-keto provides many of the benefits of DHEA supplements with none of the side effects.