1. Introduction :
Development of new drugs needs integration of diverse technologies and research area in its developmental process. The technologies in demand vary depending on the developmental stage of a new drug, and preclinical tests to evaluate the safety and efficacy of the drug is one of the most important and mandatory processes. However, the infrastructure and technologies for the preclinical tests are not well established yet in Korea, which has been a critical hurdle to attenuate the new drug development.
The “Program in Drug Development” aims at delivering fundamental knowledge and related technologies on the preclinical test to students, thereby fostering experts who are immediately ready to work in the field. The program includes overall the knowledge and technologies for the safety/toxicity test, efficacy test, animal care and disease models, quality assurance, and regulatory affairs for KFDA approval. The list of educational courses are as follow.
2. Major : Program in Drug Development
3. Faculty Members
1) Choi, Byung Hyune (최병현)
* Office : Jeong-Suk Bldg. B-Dong, 3rd Floor
*Tel : +82-32-890-0939
*E-mail :
* Homepage : (
* Educational Background :
- Ph. D : Molecular Biology / Seoul National University / Korea
- M.S. : Molecular Biology / Seoul National University / Korea
* Research Area :
- Cell Therapy
- Regenerative Medicine
- Tissue Engineering
- Gene Therapy
* Academic Works :
- Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with GM-CSF: phase I/II clinical trial. Stem Cells 25:2066-2073, 2007.
- GM-CSF inhibits glial scar formation and shows long-term protective effect after spinal cord injury. J Neurol Sci 277:87-97, 2009.
- Gene therapy of neural cell injuries in vitro using the hypoxia-inducible GM-CSF expression plasmids and water-soluble lipopolymer (WSLP). J Contr Release 133:60-67, 2009.
2) Song, Sun Uk (송순욱)
* Office : Clinical Research Center, Jeong-Suk Bldg. A-Dong, 2nd Floor
* Tel : +82-32-890-2460
* E-mail :
* Homepage :
* Educational Background :
- Ph. D : Molecular Biology / Johns Hopkins University / USA
- M.S. : Applied Molecular Biology / University of Maryland / USA
* Research Area :
- Stem Cell Therapy
- Regeneration Medicine
- Cell-mediated Gene Therapy
* Academic Works :
- Variations of Clonal Marrow Stem Cell Lines Established from Human Bone Marrow in Surface Epitopes, Differentiation Potential, Gene Expression and Cytokine Secretion. Stem Cells & Development. 17(3):451-461, 2008.
- Combined treatment with intratumoral injection of dendritic cells and topical application of imiquimod for murine melanoma. Clin Exp Dermatol. 32(5):541-549, 2007.
- Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia. Mol Ther. 13(4):705-715, 2006.
3) Hong, Soon Sun (홍순선)
* Office : Clinical Research Center, Jeong-Suk Bldg. A-Dong, 2nd Floor
* Tel : +82-32-890-3683
* E-mail :
* Homepage :
* Educational Background :
- Ph. D : Pharmaceutics / Seoul National University / Korea
- M.S. : Pharmaceutics / Seoul National University / Korea
* Research Area :
- Liver therapy using antioxidants
- Drug delivery system
- Anticancer therapy
* Academic Works :
- Deguelin inhibits hepatocellular carcinoma by antiangiogenesis and apoptosis.
Oncology Reports. 20:129-134, 2008.
- Structural basis for depletion of heat shock protein 90 client proteins by the natural
antitumor agent deguelin. Journal of the National Cancer Institute. 99: 949-961, 2007.
- Anti-angiogenic activity of Wondonin,a novel compound,inhibitshypoxia-induced
angiogenesis through hypoxia inducible factor 1 alpha. FEBS Letter. 581:4977-4982.2007.
4)Lee, Woon Kyu (이운규)
* Office : Jeong-Suk Bldg. A-Dong, 8rd Floor
*Tel : +82-32-890-1182
*E-mail :
* Educational Background :
- Ph. D : Molecular Pharmacology / The CatholicUniversity ofKorea
- M.S. : Embryology / Seoul National University / Korea
* Research Area :
- Developmental genetics
- Functional genomics
-Genetic Animal model development
* Academic Works :
-LIM-homeodomain proteins Lhx1, Lhx5, and their cofactor Ldb1 control Purkinje cell differentiation in the developing cerebellum. Proceedings of the National Academy of Sciences, USA. 104(32):13182-13186, 2007.
-Recent progress in biotechnology-base gene manipulating system to produce knock-in/out mouse models. Asian-Australasian Journal of Animal Science. 21(5):745-753, 2008
- Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Molecular and Cellular Biology. 28(15):4875-4882, 2008.
5) Kang, Ju-Hee (강주희)
* Office : Jungsuk BD 6th FL
* Tel : +82-32-890-0963
* E-mail :
* Homepage :
* Educational Background :
- Ph. D : Pharmacology / Inha University / Korea
- M.S. : Pharmacology / Inha University / Korea
* Research Area :
-Two main fields in my researches are 1) the development of strategies to treat obesity and related diseases, and 2) the pharmacogenomics related to metabolic syndrome. First, the hope is to discover novel mechanisms or molecules that could serve as potential links between inflammation and the process of metabolic syndrome, thereby defining novel targets for clinically useful pharmacological intervention.
Another goal is related to clinical pharmacogenomics. Based on the genomic tools, we make efforts to elucidate the clinical meanings of interindividual genetic variations in pharmacological intervention.
* Academic Works :
- Novelblack soy peptides with antiobesity effects: activation of leptin-like signaling and AMP-activated protein kinase.Int J Obesity.32:1161-1170,2008.
-Genetic Polymorphisms in the ABCB1 Gene and the Effects of Fentanyl in Koreans. Clin Pharmacol Ther.81:539-546,2007.
-Excessive nitric oxide attenuates leptin-mediated signal transducer and activator of transcription 3 activation. Life Sci.80:609-617,2007.
6) Lee, Don Haeng (이돈행)
*Office : Jung-Seok Bld 6th floor
*Tel : +82-32-890-2548,2246
*E-mail :
*Homepage :
*Educational Background :
- Ph.D :Internal Medicine/ Yonsei University / Korea
-M.S : Internal Medicine/ Yonsei University / Korea
*Research Area : Gastrointestinal Disease drug delivery system
*Academic Work :
- Intrahepatic Cholangiocellular Carcinoma Korean J Gastroenterol 1995;27: 679 - 689
- Drug-eluting Stent in Gastrointestinal Disease. THE KOREAN JOURNAL OF GASTROENTEROLOGY 2007:49;294-299
7) Kim, Youn Sung (김연성)
* Office : 6-412
* Tel : +82-32-860-7759
* E-mail :
* Educational Background
- B.A. Seoul National University, Seoul, Korea, 1986
- M.S. Seoul National University, Seoul, Korea (Major: Operations Management), 1989
- Ph. D. Seoul National University, Seoul, Korea (Major: Operations Management), 1997
* Professional Background
- Professor, Department of Information and Operations Management, Marshall School of Business, University of Southern California (2007.2- Present)
- Vice dean, Management Assistance Office, Inha-Industry Partnership Institute (2004.8~2006.7)
- Research director, Entrepreneurial Research Center, Kookmin Bank Research Institute (1997.3-1998.2)
* Publications for past 5 years
- Six Sigma Management for CEOs, Hankyungsa Press, 2006
- Success Rule of Malcolm Baldrige, Kimyoungsa Press, 2005
- Principles of Management Quality, Chongmoongak Press, 2005
- Service Management, Bubmoonsa Press, 2004
- Quality Management, Parkyoungsa Press, 2004
8) Lee, Dong Won (이동원)
* Office : 6-508
* Tel : +82-32-860-7766
* E-mail :
* Educational Background
- B.A. Seoul National University, Seoul, Korea, 1983
- M.S. Seoul National University, Seoul, Korea (Major: Operations Management), 1985
- Ph. D. University of Southern California, LA, U.S.A, 2003
* Professional Background
- Vice president, Inha graduate school of business administration (2005.3-2007.2)
* Publications for past 5 years
- “Developing Environmental Quality Deployment for Designing Environmentally Friendly Product,” Korea Quality Management Association, 2003, Vol.31, No.2, pp.40-50.
- “Internet As a Medium for Public Relationship Management- Why Some Company Websites Address Environmental Issues more than Others?,” Korea Service Management Association, 2003, Vol.4, No.1, pp.111-123.
- “Assessing Life-Cycle Environmental Impact: Methodology to Spur Design of Greener Products and Processes / Greener Manufacturing and Operations: From Design to Delivery and Back,” Edited by J. Sarkis, Greenleaf Publishing, 2001, pp.223-242.
9) Park, So Ra (박소라)
* Office : B dong 6 F
* Tel : +82-32-890-0922
* E-mail :
* Homepage :
* Educational Background :
- Ph. D : Physiology(Medicine) / Yonsei University / Korea
- M.S. : Physiology (Medicine) / Yonsei University / Korea
* Research Area :
- Stem cell differentiation
- Regeneration and repair of cartilage
* Academic Works :
- The effect of sonication on osteoarthritis. Part I: Effects of ultrasound on uptake of hyaluronate into the rabbit synovium/Ultrasound in Medicine &Biology 31(II): 1551-1558, 2005
- The effect of sonication on osteoarthritis. Part II: Alleviation of osteoarthritis pathogenesis by ultrasound with simultaneous hyaluronate injection/Ultrasound in Medicine & Biology 31(II):1559-1566, 2005
- Low intensity ultrasound stimulation enhances the chordrogenic differentiation in alginate bead culture of mesenchymal stem cell /Artificial organs 30(9):707-715, 2006
4. Course List
CourseCode / Course / Credits / Taught
In
English
Common courses
(Mandatory) / VR501 / Experimental Animals / 3 / X
VR502 / Principles of Pharmacology / 3 / X
VR503 / Medical Physiology / 3 / X
VR504 / Biomedical Pharmaceutics / 3 / X
VR505 / Experiments for Efficiency Evaluation / 3 / X
VR506 / Quality Control in Drug Development / 3 / X
VR507 / Clinical Trial / 3 / X
VR508 / Digestive Diseases / 3 / X
Basic courses
(Optional) / VR601 / Molecular Biology / 3 / X
VR602 / Molecular Oncology / 3 / X
VR603 / Drug Metabolism and Toxicity / 3 / X
VR604 / Principles of Toxicology / 3 / X
VR605 / Special lectures on human anatomy / 3 / X
VR606 / Special Lecture of Oncology / 3 / X
Deepening courses
(Optional) / VR701 / Stem Cell Therapy / 3 / X
VR702 / Functional Genomics / 3 / X
VR703 / Immunohistochemistry / 3 / X
VR704 / Management of Technology / 3 / X
VR705 / Corporate Innovation Strategy / 3 / X
VR706 / New Drug Development & Healthcare Industry Analysis / 3 / X
VR707 / Case Study for Healthcare Technology Commercialization Strategy / 3 / X
VR708 / Analysis of patent and technology / 3 / X