2ndSchool of Medicine Postgraduate Research Day

Thursday 11th December 2008

Education Centre, Adelaide & Meath Hospital Dublin, Incorporating the National Children’s Hospital, Tallaght

Programme

9.00amRegistration,

Foyer, Education Centre

9.30amIntroduction & Welcome

Dr. Thomas Connor,Director of Postgraduate Teaching & Learning

9.35amResearch in the School of Medicine

Dr. Aiden Corvin, Director of Research

SESSION ONE

Chair:Dr. Thomas Connor, Department of Physiology

Dr. Aideen Long, Department of Clinical Medicine

9.45amTranslational Research in Ireland

Dr. Ruth Barrington, CEO, Molecular Medicine Ireland

10.15amThe flaky tail phenotype (ft) is caused by a homozygous frameshift mutation in the murine filaggrin gene and lead to enhanced cutaneous allergen priming

Sean Saunders, Department of Clinical Medicine

10.30amNuclear receptor-mediated expression of CYP3A4 and CYP2B6 by antiretrovirals - implications for prediction of drug interaction potential and genetic variability in PXR, MDR-1, CYP3A4 and CYP2B6 in HIV infected Caucasian and Sub-Saharan African patients - benefits from a cohort approach

Jenny Svard, Department of Pharmacology & Therapeutics

10.45amHepatic inflammatory gene expression and the development of obesity-induced insulin resistance in IL-1R1 knock out mice

Orla Finucane, Department of Clinical Medicine

11.00amCOFFEE BREAK/POSTER DISPLAY

SESSION TWO

Chair:Professor Des O’Neill, Department of Medical Gerontology

Professor Marina Lynch, Department of Physiology

11.30amThe β2-adrenoceptor agonist clenbuterol activates astrocytes and reduces amyloid-β concentrations and RAGE expression in rat cortex and hippocampus

Karen Ryan, Department of Physiology

11.45amShort-term environmental enrichment enhances object recognition memory and increases the concentration of nerve growth factor, but not brain derived neurotrophic factor, in the dentate gyrus of male Wistar rats

Amy Birch, Department of Physiology

12.00pmAn Investigation into the Effects of Ursodeoxycholic acid on the Golgi Apparatus

Ruchika Sharma, Department of Clinical Medicine

12.15pmEndocannabinoids prevent lysosomal membrane destabilisation evoked by treatment with β-amyloid

Janis Noonan, Department of Physiology

12.30pmABCD scoring by non-vascular neurologists for risk stratification following suspected TIA is frequently inappropriate and inaccurable

Justin Kinsella, Department of Clinical Medicine

12.45pmIL-1 receptor type 1 knockout mice fed a high-fat diet are partially protected from an obesity-induced insulin resistance state

Elizabeth Oliver, Department of Clinical Medicine

1.00pmLUNCH/POSTER DISPLAY

SESSION THREE

Chair:Dr. John Gormley, Department of Physiotherapy

Dr. Aine Kelly, Department of Physiology

2.00pmAutonomic dysfunction: A biomarker of cognitive decline/dementia?

Orla Collins, Department of Medical Gerontology

2.15pmAntimicrobial resistance mechanisms in clinical isolates of Pseudomonas Aeruginosa

Sarah Molan, Department of Clinical Microbiology

2.30pmThe use of novel fluorescent magnetic nanocomposites for biomedical applications

Joseph Gallagher, Department of Physiology

2.45pmMolecular characterisation of antimicrobial resistant bacteraemic Escherichia coli isolates from an Irish hospital

Niamh Cooke, Department of Clinical Microbiology

3.00pmIdentifying Blood Pressure Response Subtypes Following Orthostatis Using Pattern Recognition Techniques

Ciaran Finucane, Department of Medical Gerontology

3.15pmPolymorphisms in Oxytocin Receptor and CD38 genes and Autism: Association and Functional Studies

Katherine Tansey, Department of Psychiatry

3.30pmCOFFEE BREAK/POSTER DISPLAY

SESSION FOUR

Chair:Dr. Joe Barry, Department of Public Health & Primary Care

Ms. Eilish McAuliffe, Health Policy & Management

4.00pmEffects of carbohydrate versus carbohydrate protein ingestion on subsequent resistance training performance in male rugby players

Colin Coyle, Department of Physiology

4.15pmChanging illness beliefs in poorly controlled Type 2 Diabetes: RCT of a psychological, family-based intervention

Karen Keogh, Department of Public Health & Primary Care

4.30pmDevelopment of Neural Stem Cell Therapy for Parkinson’s Disease

Dr. Maeve Caldwell, School of Medicine, University of Bristol

5.00pmWINE RECEPTION