The Paul F. Glenn/AFAR Conference on the Biology of Aging

The 31stAnnual AFAR Grantee Conference

June4 – 6, 2018

Four Seasons Biltmore Hotel

Santa Barbara, CA

DRAFT 5/14/18

Monday, June 4, 2018

3:30 - 4:00 pmRegistration/reception

Alto

4:00 – 4:10 pmWelcome

El Mar

Stephanie Lederman

Executive Director

American Federation for Aging Research

David Sinclair, PhD

Board Member, American Federation for Aging Research and Professor, Department of Genetics

Harvard Medical School

Co-director, Paul F. Glenn Center of Biological Mechanisms

of Aging

4:10 – 5:10 pmBIG and Midcareer Presentations

“Targeting mitochondrial redox stress to improve in vivo energetics and exercise performance with age”

David Marcinek, PhD (15 BIG)

Associate Professor

University of Washington

“Cellular recycling: role of autophagy in aging and disease.”

Malene Hansen, PhD (14 Midcareer)

Associate Dean of Student Affairs, SBP Graduate School

Professor, Development, Aging and Regeneration Program

Sanford-Burnham-Prebys Medical Discovery Institute

5:10 – 5:30 pmBreak

5:30 – 6:00pm“Mitochondrial energetics and aging: lessons from

serendipity in science”

Peter Rabinovitch, MD, PhD

Professor and Vice Chair of Research,

University of Washington

6:00 – 6:30 pm“Targeting Healthspan: Functional Genetic Variation in Human Aging and Longevity”

Yousin Suh, PhD

Professor

Albert Einstein College of Medicine

6:30 – 7:00 pm“Questioning the immutability of aging”

David Sinclair, PhD

Professor, Department of Genetics

Harvard Medical School

Co-director, Paul F. Glenn Center of Biological Mechanisms

of Aging

7:00– 8:30 pmDinner

El Mar

8:30 – 9:30 pmSocial gathering, with dessert, coffee and wine

Alto

Glenn Workshop on the Biology of Aging

Back to Basics: Explaining The Obvious

Workshop Moderator: Kevin Lee

Joint meeting with the AFAR Grantee Conference and the Glenn Workshop

Tuesday, June 5, 2018

7:30 – 8:15 am Breakfast

La Marina

8:30 – 8:40 am Welcome and opening remarks

La VerandaKevin Lee, PhD

Senior Scientific & Programmatic Advisor,

Glenn Foundation for Medical Research

8:40 – 9:00 am“How do you explain aging?”

Mark Collins,

President, Glenn Foundation for Medical Research

9:00 – 9:40 am "Primary Prevention with a Capital P"

Jay Olshansky, PhD,

Professor,

School of Public Health University of Illinois at Chicago

9:40 – 10:20 am “Sex differences as an investigative tool in aging research”

Steven Austad, PhD,

Distinguished Professor, Department Chair,

Department of Biology,

Director, UAB Nathan Shock Center of Excellence in the Basic Biology of Aging,

University of Alabama, Birmingham

10:20 – 10:50 am Break

10:50-11:30 am “Dissecting sex differences in aging and neurodegenerative disease”

Dena Dubal, MD, PhD

Associate Professor,

David A. Coulter Endowed Chair in Aging and Neurodegenerative Disease,

Department of Neurology and Weill Institute for Neurosciences,

University of California, San Francisco

11:30 am – 12:10 pm Roberta Diaz Brinton, PhD, University of Arizona

12:10 – 1:10 pm Lunch

1:10 – 1:50 pm “Is “Time-restricted eating” a practical framework integrating circadian rhythms, nutrient sensing, and energy homeostasis to increase healthy lifespan?”

Satchidananda Panda, PhD,

Professor, Regulatory Biology Laboratory,

The Salk Institute for Biological Studies

1:50 – 2:30 pm “Systems Genetics Identifies Resilience Factors in Normal Cognitive Aging and Alzheimer’s”

Catherine Kaczorowski, PhD,

Associate Professor,

Evnin Family Endowed Chair in Alzheimer’s Research,

The Jackson Laboratory

2:30 -2:50 pm Break

2:50 – 3:30 pm “Cholesterol Homeostasis in Aging and Disease”

Raj Apte, MD, PhD,

Paul A. Cibis Distinguished Professor of Ophthalmology

Professor of Developmental Biology and Medicine

Director of Translational Research and Jeffrey Fort Innovation fund

Washington University School of Medicine

3:30 – 5:30 pm AFAR Grantee Poster Session

Loggia BallroomKindly remove your poster at the conclusion of the session.

6:00 – 7:00 pm Reception

La Pacifica Terrace

7:00 – 9:00pm Dinner and Dinner Speaker

La Pacifica"Science in the Age of Celebrity”

Timothy Caulfield, LLM, FRSC, FCAHS

Canada Research Chair in Health Law & Policy

Trudeau Fellow and Professor, Faculty of Law and School of Public Health

Research Director, Health Law Institute, University of Alberta

Wednesday June 6, 2018

8:00 – 8:45 am Breakfast

La Marina

Adjourn

Major Sponsors of AFAR Grant Programs

The Glenn Foundation for Medical Research

The Rosalinde and Arthur Gilbert Foundation

The AFAR Board of Directors

Anonymous

Proceeds from AFAR's 2017 Luncheon

The James A. and Dorothy R. Brunn Foundation

David W. Gore

The Hearst Foundation

Diana Jacobs Kalman

Neurosciences Education and Research Foundation (NERF)

Diane Nixon

The Irving S. Wright Endowment