1: Williams H, Crompton RA, Thomason HA, Campbell L, Singh G, Mcbain AJ, Cruickshank SM

1: Williams H, Crompton RA, Thomason HA, Campbell L, Singh G, McBain AJ, Cruickshank SM, Hardman MJ. Cutaneous Nod2 expression regulates the skin microbiome and wound healing in a murine model. J Invest Dermatol. 2017 Jun 21. doi: 10.1016/j.jid.2017.05.029. [Epub ahead of print] PubMed PMID: 28647345.

2: Yeung CC, Holmes DF, Thomason HA, Stephenson C, Derby B, Hardman MJ. An ex vivo porcine skin model to evaluate pressure-reducing devices of different mechanical properties used for pressure ulcer prevention. Wound Repair Regen. 2016 Nov;24(6):1089-1096. doi: 10.1111/wrr.12481. Epub 2016 Oct 18. PubMed PMID: 27717144.

3: Wilkinson HN, McBain AJ, Stephenson C, Hardman MJ. Comparing the Effectiveness of Polymer Debriding Devices Using a Porcine Wound Biofilm Model. Adv Wound Care (New Rochelle). 2016 Nov 1;5(11):475-485. PubMed PMID: 27867752; PubMed Central PMCID: PMC5105345.

4: Garcin CL, Huttner KM, Kirby N, Schneider P, Hardman MJ. Ectodysplasin A Pathway Contributes to Human and Murine Skin Repair. J Invest Dermatol. 2016 May;136(5):1022-30. doi: 10.1016/j.jid.2015.09.002. Epub 2016 Jan 29. PubMed PMID: 26829034; PubMed Central PMCID: PMC4967474.

5: Garcin CL, Ansell DM, Headon DJ, Paus R, Hardman MJ. Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization. Stem Cells. 2016 May;34(5):1377-85. doi: 10.1002/stem.2289. Epub 2016 Feb 2. PubMed PMID: 26756547; PubMed Central PMCID: PMC4985639.

6: Crompton R, Williams H, Ansell D, Campbell L, Holden K, Cruickshank S, Hardman MJ. Oestrogen promotes healing in a bacterial LPS model of delayed cutaneous wound repair. Lab Invest. 2016 Apr;96(4):439-49. doi: 10.1038/labinvest.2015.160. Epub 2016 Feb 8. PubMed PMID: 26855364.

7: Ansell DM, Hardman MJ. Do not be alarmed: understanding IL33-ST2 signalling in wound repair. ExpDermatol. 2016 Jan;25(1):22-3. doi: 10.1111/exd.12887. Epub 2015 Dec 11. PubMed PMID: 26519250.

8: Cooper NH, Balachandra JP, Hardman MJ. Global Gene Expression Analysis in PKCα-/- Mouse Skin Reveals Structural Changes in the Dermis and Defective Wound Granulation Tissue. J Invest Dermatol. 2015 Dec;135(12):3173-82. doi: 10.1038/jid.2015.338. Epub 2015 Sep 9. PubMed PMID: 26354149.

9: Campbell L, Emmerson E, Williams H, Saville CR, Krust A, Chambon P, Mace KA, Hardman MJ. Estrogen receptor-alpha promotes alternative macrophage activation during cutaneous repair. J Invest Dermatol. 2014 Sep;134(9):2447-57. doi: 10.1038/jid.2014.175. Epub 2014 Apr 9. PubMed PMID: 24769859.

10: Mills SJ, Farrar MD, Ashcroft GS, Griffiths CE, Hardman MJ, Rhodes LE. Topical photodynamic therapy following excisional wounding of human skin increases production of transforming growth factor-β3 and matrix metalloproteinases 1 and 9, with associated improvement in dermal matrix organization. Br J Dermatol. 2014 Jul;171(1):55-62. doi: 10.1111/bjd.12843. Epub 2014 Jun 24. PubMed PMID: 24471979.

11: Ansell DM, Campbell L, Thomason HA, Brass A, Hardman MJ. A statistical analysis of murine incisional and excisional acute wound models. Wound Repair Regen. 2014 Mar-Apr;22(2):281-7. doi: 10.1111/wrr.12148. PubMed PMID: 24635179; PubMed Central PMCID: PMC4309476.

12: Bannon P, Wood S, Restivo T, Campbell L, Hardman MJ, Mace KA. Diabetes induces stable intrinsic changes to myeloid cells that contribute to chronic inflammation during wound healing in mice. Dis Model Mech. 2013 Nov;6(6):1434-47. doi: 10.1242/dmm.012237. Epub 2013 Sep 18. PubMed PMID: 24057002; PubMed Central PMCID: PMC3820266.

13: Campbell L, Saville CR, Murray PJ, Cruickshank SM, Hardman MJ. Local arginase 1 activity is required for cutaneous wound healing. J Invest Dermatol. 2013 Oct;133(10):2461-70. doi: 10.1038/jid.2013.164. Epub 2013 Apr 3. PubMed PMID: 23552798; PubMed Central PMCID: PMC3778883.

14: Emmerson E, Rando G, Meda C, Campbell L, Maggi A, Hardman MJ. Estrogen receptor-mediated signalling in female mice is locally activated in response to wounding. Mol Cell Endocrinol. 2013 Aug 15;375(1-2):149-56. doi: 10.1016/j.mce.2013.05.015. Epub 2013 May 29. PubMed PMID: 23727624.

15: Campbell L, Williams H, Crompton RA, Cruickshank SM, Hardman MJ. Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response. J Pathol. 2013 Jan;229(1):121-31. doi: 10.1002/path.4095. PubMed PMID: 22951952.

16: Meier NT, Haslam IS, Pattwell DM, Zhang GY, Emelianov V, Paredes R, Debus S, Augustin M, Funk W, Amaya E, Kloepper JE, Hardman MJ, Paus R. Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin. PLoS One. 2013 Sep 2;8(9):e73596. doi: 10.1371/journal.pone.0073596. eCollection 2013. PubMed PMID: 24023889; PubMed Central PMCID: PMC3759422.

17: Emmerson E, Campbell L, Davies FC, Ross NL, Ashcroft GS, Krust A, Chambon P, Hardman MJ. Insulin-like growth factor-1 promotes wound healing in estrogen-deprived mice: new insights into cutaneous IGF-1R/ERα cross talk. J Invest Dermatol. 2012 Dec;132(12):2838-48. doi: 10.1038/jid.2012.228. Epub 2012 Jul 19. PubMed PMID: 22810305.

18: Ansell DM, Holden KA, Hardman MJ. Animal models of wound repair: Are they cutting it? ExpDermatol. 2012 Aug;21(8):581-5. doi: 10.1111/j.1600-0625.2012.01540.x. PubMed PMID: 22775993.

19: Thomason HA, Cooper NH, Ansell DM, Chiu M, Merrit AJ, Hardman MJ, Garrod DR. Direct evidence that PKCα positively regulates wound re-epithelialization: correlation with changes in desmosomal adhesiveness. J Pathol. 2012 Jul;227(3):346-56. doi: 10.1002/path.4016. Epub 2012 May 8. PubMed PMID: 22407785.

20: Emmerson E, Hardman MJ. The role of estrogen deficiency in skin ageing and wound healing. Biogerontology. 2012 Feb;13(1):3-20. doi: 10.1007/s10522-011-9322-y. Epub 2011 Mar 3. Review. PubMed PMID: 21369728.

21: Ansell DM, Kloepper JE, Thomason HA, Paus R, Hardman MJ. Exploring the "hair growth-wound healing connection": anagen phase promotes wound re-epithelialization. J Invest Dermatol. 2011 Feb;131(2):518-28. doi: 10.1038/jid.2010.291. Epub 2010 Oct 7. PubMed PMID: 20927125.

22: Gonzalez JS, Hardman MJ, Boulton AJ, Vileikyte L. Coping and depression in diabetic foot ulcer healing: causal influence, mechanistic evidence or none of the above? Diabetologia. 2011 Jan;54(1):205-6. doi: 10.1007/s00125-010-1926-2. Epub 2010 Oct 13. PubMed PMID: 20938635.

23: Gilliver SC, Emmerson E, Bernhagen J, Hardman MJ. MIF: a key player in cutaneous biology and wound healing. ExpDermatol. 2011 Jan;20(1):1-6. doi: 10.1111/j.1600-0625.2010.01194.x. Review. PubMed PMID: 21158933.

24: Campbell L, Emmerson E, Davies F, Gilliver SC, Krust A, Chambon P, Ashcroft GS, Hardman MJ. Estrogen promotes cutaneous wound healing via estrogen receptor beta independent of its antiinflammatory activities. J Exp Med. 2010 Aug 30;207(9):1825-33. doi: 10.1084/jem.20100500. Epub 2010 Aug 23. PubMed PMID: 20733032; PubMed Central PMCID: PMC2931162.

25: Emmerson E, Campbell L, Ashcroft GS, Hardman MJ. The phytoestrogen genistein promotes wound healing by multiple independent mechanisms. Mol CellEndocrinol. 2010 Jun 10;321(2):184-93. doi: 10.1016/j.mce.2010.02.026. Epub 2010 Mar 1. PubMed PMID: 20193736.

26: Waite A, Gilliver SC, Masterson GR, Hardman MJ, Ashcroft GS. Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice. Br J Anaesth. 2010 Jun;104(6):768-73. doi: 10.1093/bja/aeq093. Epub 2010 Apr 24. PubMed PMID: 20418532; PubMed Central PMCID: PMC2867659.

27: Gilliver SC, Emmerson E, Campbell L, Chambon P, Hardman MJ, Ashcroft GS. 17beta-estradiol inhibits wound healing in male mice via estrogen receptor-alpha. Am J Pathol. 2010 Jun;176(6):2707-21. doi: 10.2353/ajpath.2010.090432. Epub 2010 May 6. PubMed PMID: 20448060; PubMed Central PMCID: PMC2877833.

28: Hepworth MR, Hardman MJ, Grencis RK. The role of sex hormones in the development of Th2 immunity in a gender-biased model of Trichurismuris infection. Eur J Immunol. 2010 Feb;40(2):406-16. doi: 10.1002/eji.200939589. PubMed PMID: 19950176; PubMed Central PMCID: PMC3549561.

29: Byrne C, Avilion AA, O'Shaughnessy RF, Welti JC, Hardman MJ. Whole-mount assays for gene induction and barrier formation in the developing epidermis. Methods Mol Biol. 2010;585:271-86. doi: 10.1007/978-1-60761-380-0_19. PubMed PMID: 19908010.

30: Emmerson E, Campbell L, Ashcroft GS, Hardman MJ. Unique and synergistic roles for 17beta-estradiol and macrophage migration inhibitory factor during cutaneous wound closure are cell type specific. Endocrinology. 2009 Jun;150(6):2749-57. doi: 10.1210/en.2008-1569. Epub 2009 Feb 5. PubMed PMID: 19196797.

31: Gilliver SC, Ruckshanthi JP, Hardman MJ, Zeef LA, Ashcroft GS. 5alpha-dihydrotestosterone (DHT) retards wound closure by inhibiting re-epithelialization. J Pathol. 2009 Jan;217(1):73-82. doi: 10.1002/path.2444. PubMed PMID: 18855875.

32: Gilliver SC, Ruckshanthi JP, Hardman MJ, Nakayama T, Ashcroft GS. Sex dimorphism in wound healing: the roles of sex steroids and macrophage migration inhibitory factor. Endocrinology. 2008 Nov;149(11):5747-57. doi: 10.1210/en.2008-0355. Epub 2008 Jul 24. PubMed PMID: 18653719.

33: Hardman MJ, Emmerson E, Campbell L, Ashcroft GS. Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomized female mice. Endocrinology. 2008 Feb;149(2):551-7. Epub 2007 Nov 1. PubMed PMID: 17974625.

34: Hardman MJ, Ashcroft GS. Estrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly. Genome Biol. 2008;9(5):R80. doi: 10.1186/gb-2008-9-5-r80. Epub 2008 May 13. PubMed PMID: 18477406; PubMed Central PMCID: PMC2441466.

35: Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ. Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch. Nat Genet. 2006 Nov;38(11):1329-34. Epub 2006 Oct 15. PubMed PMID: 17041603.

36: Gilliver SC, Ashworth JJ, Mills SJ, Hardman MJ, Ashcroft GS. Androgens modulate the inflammatory response during acute wound healing. J Cell Sci. 2006 Feb 15;119(Pt 4):722-32. Epub 2006 Jan 31. PubMed PMID: 16449322.

37: Hardman MJ, Waite A, Zeef L, Burow M, Nakayama T, Ashcroft GS. Macrophage migration inhibitory factor: a central regulator of wound healing. Am J Pathol. 2005 Dec;167(6):1561-74. PubMed PMID: 16314470; PubMed Central PMCID: PMC1613193.

38: Mills SJ, Ashworth JJ, Gilliver SC, Hardman MJ, Ashcroft GS. The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors. J Invest Dermatol. 2005 Nov;125(5):1053-62. PubMed PMID: 16297209.

39: Jackson B, Tilli CM, Hardman MJ, Avilion AA, MacLeod MC, Ashcroft GS, Byrne C. Late cornified envelope family in differentiating epithelia--response to calcium and ultraviolet irradiation. J Invest Dermatol. 2005 May;124(5):1062-70. PubMed PMID: 15854049.

40: Hardman MJ, Liu K, Avilion AA, Merritt A, Brennan K, Garrod DR, Byrne C. Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation. Mol Cell Biol. 2005 Feb;25(3):969-78. PubMed PMID: 15657425; PubMed Central PMCID: PMC544013.

41: Byrne C, Hardman MJ. Whole-mount assays for gene induction and barrier formation in the developing epidermis. Methods Mol Biol. 2005;289:127-36. PubMed PMID: 15502178.

42: Merritt AJ, Berika MY, Zhai W, Kirk SE, Ji B, Hardman MJ, Garrod DR. Suprabasaldesmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation. Mol Cell Biol. 2002 Aug;22(16):5846-58. PubMed PMID: 12138195; PubMed Central PMCID: PMC133994.

43: Marshall D, Hardman MJ, Nield KM, Byrne C. Differentially expressed late constituents of the epidermal cornified envelope. Proc Natl AcadSci U S A. 2001 Nov 6;98(23):13031-6. PubMed PMID: 11698679; PubMed Central PMCID: PMC60819.

44: Marshall D, Hardman MJ, Byrne C. SPRR1 gene induction and barrier formation occur as coordinated moving fronts in terminally differentiating epithelia. J Invest Dermatol. 2000 May;114(5):967-75. PubMed PMID: 10771479.

45: Hardman MJ, Moore L, Ferguson MW, Byrne C. Barrier formation in the human fetus is patterned. J Invest Dermatol. 1999 Dec;113(6):1106-13. PubMed PMID: 10594759.

46: Hardman MJ, Sisi P, Banbury DN, Byrne C. Patterned acquisition of skin barrier function during development. Development. 1998 Apr;125(8):1541-52. PubMed PMID: 9502735.