附件1: IBRO COURSE IN NEUROSCIENCE

MEDICALCOLLEGEof QingdaoUniversity

Qingdao, China

July 15-23, 2009.

Organizers:

Junxia Xie, Professor of Physiology and President, The Medical College of Qingdao, China

U. J. McMahan, Professor and Head of Biology, Texas A&M University, USA/

Professor of Neurobiology and of Structural Biology Emeritus, Stanford University, USA

FacultyLecturers:

Prof. Alasdair Gibb, Department of Pharmacology, UniversityCollegeLondon, London, UK

Prof. Jack McMahan, Department of Biology, TexasA&MUniversity,College Station, Texas,USA

Prof. John Nicholls, Department of Neurobiology, InternationalSchool for Advanced Studies (SISSA), Trieste, Italy.

Prof. Noreen Reist, Division of Neuroscience, ColoradoStateUniversity, Fort Collins, Colorado, USA.

Prof. Shlomo Rotshenker, Department of Anatomy/Cell Biology, HebrewUniversityMedicalSchool, Jerusalem, Israel.

Thirty-seven lectures last for about 50 minutes each. Conferences are used for discussion of questions that arise from the lectures and consist of small groups that rotate day by day to different lecturers. Students will have the opportunity to present 10 min. talks and write abstracts on their own work if they wish. Tutorials on how to present the talks according to the format of international meetings are given at the end of each day. There will also be a discussion about how to seek pre- and postdoctoral training opportunities.

Schedule (subject to change):

Wednesday, July 15.

8:30 Introduction:Junxia Xie, Jack McMahan

9:00 Principles of Signaling (JN)

10:00 Coffee break

10:30 The cellular composition of the PNS and CNS: Neuronal and non-neuronal cells. (SR)

11:30 Break

11:45 Synaptic transmission overview: Physiology and pharmacology. (AG)

12:45 Lunch

2:00 Conferences

3:00 Synaptic transmission overview: Structure. (JM)

4:00 Coffee Break

4:30 Synaptic transmission overview: Synaptic vesicle cycle. (NR)

5:30 Tutorials on presenting 10 min talks/abstracts.

Thursday, July 16.

9:00 The regulation of axonal growth - regeneration - by repulsion and attraction signals from the environment. (SR

10:00 Coffee break

10:30 The active zone. (JM)

11:30 Break

11:45 Presynaptic molecules - purification and cloning. (NR)

12:45 Lunch

2:00 Conferences

3:00 Generation of synaptic currents and synaptic potentials (AG)

4:00 Coffee Break

4:30 Structural and functional organization of the visual system I. (JN)

5:30 Tutorials on presenting 10 min talks/abstracts.

Friday, July 17.

9:00 PNS Wallerian degeneration I: the inflammatory response. (SR)

10:00 Coffee Break

10:30 Active zone material (JM)

11:30 Break

11:45 Model systems for studying vesicle behavior. (NR)

12:45 Lunch

2:00 Conferences

3:00 Generation of synaptic currents and synaptic potentials (AG)

4:00 Coffee Break

4:30 Structural and functional organization of the visual system II (JN)

5:30 Tutorials on presenting 10 min talks/abstracts.

Saturday, July 18.

9:00 Structural and functional organization of the visual system III (JN)

10:00 Coffee Break

10:30 G protein-coupled neurotransmitter receptors, secondmessengers and modulation of ion channel activity. (AG)

11:30 Break

11:45The SNARE hypothesis. (NR)

12:45 Lunch

2:00 Conferences

3:00 Macromolecular structure of synaptic vesicles and its role in synaptic transmission. (JM)

4:00 Coffee Break

4:30 PNS Wallerian degeneration II: Neurotrophic factor(s) production, neuropathic pain. (SR)

5:30 Tutorials on presenting 10 min talks/abstracts.

Sunday, July 19. Free Day

Monday, July 20.

9:00 Development of the nervous systemI. (JN)

10:00 Coffee Break

10:30 Time course of synaptic currents (AG)

11:30 Break

11:45 The response of the adult CNS to axonal injury: creation of an environment non-permissive to regeneration. (SR)

12:45 Lunch

2:00 Conferences

3:00 Docking and priming of synaptic vesicles. (NR)

4:00 Coffee Break

4:30 Molecular organization of the synaptic cleft and postsynaptic apparatus. (JM)

5:30 Tutorials on presenting 10 min talks/abstracts.

Tuesday, July 21.

9:00 Development of the nervous system II(JN)

10:00 Coffee Break

10:30 Integration of synaptic activity. (AG)

11:30 Break

11:45 Calcium triggered vesicle fusion. (NR)

12:45 Lunch

2:00 Conference

3:00 Regeneration of the immature spinal cord after injury. (JN)

4:00 Coffee Break

4:30 Regeneration of the neuromuscular juction. (JM)

5:30 Tutorials on presenting 10 min talks/abstracts.

Wednesday, July 22.

9:00 Origin of respiratory rhythm. (JN)

10:00 Coffee Break

10:30 Macrophage and microglia activation in injury and disease in the nervous system. (SR)

11:30 Break

11:45 Recycling of synaptic vesicles. (NR)

12:45 Lunch

2:00 Conferences

3:00 Synaptic activity and the brain's energy budget. (AG)

4:00 Coffee Break

4:30 Discovery of agrin and its role in neuromuscular junction development and regeneration. (JM)

5:30 Tutorials on presenting 10 min talks/abstracts.

Thursday, June 23.

9:00 The Vertebrate Retina: Information Processing and Underlying Mechanisms. I.

10:00 Coffee Break

10:30 The Vertebrate Retina: Information Processing and Underlying Mechanisms. II.

11:30 Break

11:45 Student Presentations.

1:00 Lunch

2:00 Student Presentations.

4:00 Lectures on the nervous system by colleagues from host institution.

General discussion about options for and how to seek pre- and postdoctoral training.

E-mail addresses of lecturers:

Alasdair Gibb <>

Jack McMahan <

John Nicholls

Noreen Reist <>

Shlomo Rotshenker <