Supplemental Instruction
Iowa State University / Leader: / Chelsea P
Course: / AnS 214
Instructor: / Dr. Koltes
Date: / 9/11/17
A. The Stomach
1) Digestion of Macronutrients:
Carbohydrates Protein Lipid
WHERE BEGIN:
ENZYME INVOLVED:
2) The three parts of the stomach are the ______, which is the entry point into the stomach, the ______, the dome-shaped region below the diaphragm, and the ______, which is the largest portion of the stomach. Chyme exits the stomach into the ______.
3) For each of the glands below, list their secretory products.
Chief cells:
Parietal cells:
G enteroendocrine cells:
Goblet cells:
B. HCl production in the stomach.
4) This process takes place in what cell type?
5) What enzyme is responsible for the eventual formation of H ions?
6) Pepsinogen is secreted in the inactive form. The inactive enzyme, or ______, is activated by the presence of ______, by the removal of an inhibiting peptide chain.
(Peptide chain blocks enzyme active site, removal of peptide allows interaction between enzyme site and protein)
7) Fill in the diagram below
8) The ingestion of food causes an ______in pH. This activates ______in the gastric pits to produce ______.
This hormone, causes ______to produce HCl, and chief cells to produce the zymogen ______. When combined, these two substrates induce the formation of the active enzyme ______.
This is an example of FEED ______REGULATION!
How is this Cycle stopped? (Hint: Small Intestine involvement)
C) Regulation of gastric motility.
9) Name and define activating factor for the 3 phases of gastric function.
1. ______:
2. ______:
3. ______:
D) Liver and Gallbladder
10) Bile, while produced by the ______is stored in the ______. It is an ______solution, and consists of cholesterol derived ______, the pigment ______, as well as cholesterol, neutral fats, phospholipids and electrolytes.
E) Features of the Small Intestine
11) Name and define the 3 structural features of the SI that increase its surface area.